Cialis
Cialis Side Effects
Like all medications, Cialis has side effects that affect some men that take this medication. Some common side effects of Cialis are:
Notably, Cialis has fewer side effects than other medications used to treat erectile dysfunction. In fact, many men who experience nasal congestion, stomach pain, nausea and diarrhoea with other drugs find that Cialis doesn’t give them these symptoms.
What is Cialis?
Cialis contains the active ingredient tadalafil and is a medication used to treat erectile dysfunction. It offers particularly long lasting effects in comparison to the other treatment options available and can produce results for up to 36 hours after taking a single pill in helping you to get and keep an erection.
How to take Cialis?
Cialis 36-Hour and Cialis Daily both contain the same medication but have different purposes and are there for taken differently.
How to take Cialis 36 Hour :
Take 1 tablet whole with a glass of water 30 minutes to 1 hour before planning to be sexually active. You can take it with or without food, but keep in mind it may take longer to work if taken with a heavy meal. You only need to take Cialis when you are going to be sexually active.
How to take Cialis Daily :
Take 1 tablet whole with a glass of water at the same time each day. You may take it with or without food, as it will not affect how well it works. It is important that you take it regularly every day to ensure you get the full benefit of the medication, so it can be helpful to incorporate it into your daily routine (e.g. with coffee at breakfast).
What dose should you take?
Cialis 36-Hour comes in two doses, either 10 mg or 20 mg. It is recommended to begin with the 10 mg tablet and continue if this is effective, as lower doses have less chance of side effects. If you find it is not having the desired effect on your erection after several separate attempts, you can try increasing the dose to 20 mg. If you are still not satisfied with the results, talk to your doctor about other medication solutions for you.
Cialis Daily is available in two strengths of 2.5 mg and 5 mg. Usually men begin with the 5 mg dose and adjust as needed. If you find that you are experiencing side effects or the 5 mg seems to be too strong for you, you can try decreasing the dose to 2.5 mg.
How long does it take to work?
Cialis has a benefit over other erectile dysfunction medications because it is so quick to work, often effective enough to allow sexual intercourse just 20 minutes after taking the pill. This is because it is absorbed into the body more easily and goes into action sooner. While you can take Cialis with or without food, it may take slightly longer to work if you take it with or soon after a large meal.
For Cialis Daily, it can take up to 5 days for the full effect to come into effect, as the low dose builds up gradually. However, after this time it will work continuously.
How long will it last?
Cialis has an extremely long duration of action in comparison to other erectile dysfunction medications and has been noted to work up to 36 hours after taking the pill.
Cialis Daily goes one step further to provide you with a ceaseless solution to erectile dysfunction. As it is a daily medication, you will always be ready for sexual activity.
Alternatives to Cialis
Counselling
For many men suffering from erectile dysfunction the primary cause may be related to psychological issues and not physical ones.
In these cases, counselling can prove to be a very effective form of treatment. Talking with a mental health professional will help to address issues of stress, anxiety or depression, which can all contribute to erectile dysfunction. For further information contact your GP.
Other ED Medications
We offer a range of ED medications. Visit our full range here .
Patient Information Leaflet
Always read the patient information leaflet before commencing treatment. Patient information can be found here.
Why buy Cialis from India?
Cialis that is also called Tadalafil is used for successful treatment of erectile dysfunction. One of Indian pharmaceutical companies distributes the medication under the name Tadacip. Indian Cialis produced by Cipla Limited can be acquired in doses 10 and 20 mg.
As for the production of generic Cialis India takes one of the leading positions in the world. Buying Cialis from India you are able to get high quality product at a reasonable price. Some people find it too costly to buy non-generic Cialis. Therefore medicine from India can be a good alternative to more expensive options.
It is noteworthy to mention that Cialis was approved by Federal Drug Administration in 2003 and when you take generic preparation you do not have FDA safety guarantee. People with unhealthy heart and the ones who take some other treatment should not take Cialis without prescription.
If you feel dizzy, seek, have running nose, stomach problems, pain in the back and muscles, or something else after you started treatment with Cialis you should tell your doctor about it.
There were reports about loss of vision too. Stop taking pills if you have the problems of this type.
Not all men are able to take Cialis. When patients take some medication that contains nitrates it can pose threat to health.
In case you took the medication and it caused side effects then you should know that the chemical will stay in your organism for a couple of days.
Myths about Cialis
- There are some myths that are connected with Cialis. Some men consider that it is able to cure erectile dysfunction but this is wrong. Erectile problem can be caused by some psychological problem or stress and should be removed from the life of the patient otherwise the same problem appear again.
- Opposing to common belief, Cialis doesn’t increase sexual desire of the person and sexual stimulation is required to get the desired effect. It is better to take measures as soon as possible when the problem occurred. If you are not able to buy Cialis it is quite affordable to order Cialis online and get pleasure from your intimate life.
Available dosages: 2.5mg, 5mg, 10mg, 20mg, 40mg
Individual results may vary. Information and statements regarding dietary supplements have not been evaluated by the Food and Drug Administration.
This product is not intended to diagnose, treat, cure, or prevent any disease.
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Where Are The Best Places to Buy Cialis Online?
Just like Viagra, people always ask me “Where is the best place to buy Cialis online?” Before writing this page, we investigated the top websites that sell Cialis online. We keep this information up-to-date, so all shoppers should find the Cialis costs to be current. After doing research we found out that convenience, privacy, and Authentic Medications are the reason shoppers chose some websites over others.
Who Does CoreyNahman.com Recommend?
Stay away from the bootlegs. If you are looking for genuine, brand-name Cialis Online manufactured by Eli Lilly, I recommend AccessRx.com. They have been in business since 1998. They are located in the USA in Tempe Arizona. They offer overnight shipping, and they keep their Cialis cost reasonable.
They have a 24 hour telephone number for customer service. They even have licensed physicians and pharmacists on staff to answer your medical questions.
Their prices are higher than the generics but you are assured of getting brand-name, American, FDA-Approved Cialis (and other medications) delivered to your door in a couple of days without having to go to a doctor and provide a co-pay.
If you plan to buy Cialis online, definitely check out AccessRx before you make a decision.
Who is Buying Cialis Online
More and more people are choosing to buy Cialis online. In 2003 worldwide Cialis sales were $203.3 million. According to Eli Lilly, in 2008 worldwide Cialis sales jumped to $1.44 billion. a 700% increase since it was launched in the United States!
Cialis’ popularity is catching up to Viagra (which sold $1.934 billion worldwide in 2008). This is the first time Cialis is within $500 million in sales to Viagra worldwide. In 2008 daily Cialis was launched. which should boost Cialis sales even further towards reaching Viagra.
Since so many people are buying Cialis, it is a tempting pill for unscrupulous online merchants to bootleg or make counterfeit copies of, with the eye on making a quick dollar.
Q: Is there a generic Cialis?
A: No
There is no such thing as an FDA approved generic Cialis. The Cialis patent is good until at least 2015 (source = Eli Lilly 2009 annual report, p 50). This means that Lilly has a legal monopoly on all versions of Cialis.
If you see a website advertising generic Cialis for sale, that means it is an unapproved, unauthorized bootleg version or an outright counterfeit pill. As mentioned earlier, the cost of Cialis that is authentic and approved by the FDA is more than illegal “generic” Cialis.
Q: What if I tried generic Cialis and it worked?
A: If you buy “generic” Cialis online, it may work. BUT.
you have no way of telling for sure what the active ingredient is or how much is present. You might be paying for a 20 mg dose but only getting 7mg or 8mg. Or you might be getting a dangerously high dose without knowing it.
The tablets may contain tadalafil (the active ingredient in Cialis) but they may contain something like silendafil (the active ingredient in Viagra or vardenafil the active ingredient in Levitra). It’s a crapshoot.
The only way to tell for sure would be for you to send the pills out to a pharmaceutical laboratory for a chemical analysis, but unless you are a scientist or a CSI expert this is not a realistic option. When you buy Cialis online that is sold as “generic,” you become your own guinea pig and you hope for the best. Although the your Cialis cost will be higher for the authentic version, you will have peace of mind knowing that the medication is safe and effective.
Q: If it’s not legitimate, why do they sell it?
A: The number of people sell fake Cialis online, outnumber the agencies that regulate this type of thing and the government can’t keep up.
The government considers generic Cialis to be an illegal substance. They are concerned about public health and safety issues, particularly since many non-regulated internet pharmacies sell you pharmaceuticals without a doctor’s prescription.
They don’t go after the people who buy generic Cialis online but postal authorities will interdict it at the border whenever possible. Every once in a while they go after the major players and shut down their operations.
The sellers are usually charged with mail fraud and or conspiracy to introduce misbranded drugs into interstate commerce in violation of the Federal Food, Drug, and Cosmetic Act .
Q: Where is the best place to buy Cialis Online?
A: There is no one best place to buy Cialis online but there are red flags for spotting scam Cialis sellers:
- The Cialis price should be realistic. You get what you pay for. Genuine, FDA approved Cialis should cost at least $38 per pill. If you are seeing offers for $3.00 or $4.00 per dose it is a guarantee that you are not getting the real thing.
- Google the operation that is selling the Cialis online. Do a little detective work. If they are selling shady products, or they have ripped people off in the past there is a good chance that someone has complained about them on a message board or in a blog. Google their phone number, their address, the name of the website, etc. You would be surprised to see what turns up.
- Lots of pharmacies selling Cialis online pretend to be American or Canadian but are actually located in developing nations, particularly India, Mexico and the Caribbean Basin. You want to screen out these non-North American operations.
The online pharmacy should have a physical address (not a just P.O. box) in the Unites Stated or Canada and a working telephone number. Call the number and test it out. Speak with a customer service representative. Ask a few questions such as, “what is your shipping policy? What is your return policy? What is the name of your supervising pharmacist? What is your pharmacy license number”. They should answer your questions courteously in perfect English. If they sound fishy on the phone stay away.
- Their ad should purport to sell “genuine Cialis”, “FDA approved Cialis” or “Brand Name Cialis”.
- If the ad says generic Cialis, chewable Cialis, Cialis strips, liquid or gelcaps this is a big red flag since as we have discussed above there is no such thing as generic Cialis. Generic Cialis or Cialis in any formulation other than tablets mean bootlegged product or a product that contains no active ingredient.
- A prescription should be required. If they are a reputable outfit, You should be required to do one of the following:
(A) Have one of their doctors examine you via a questionnaire or an online examination.
(B) Mail or fax them a prescription.
(C) Have them call your doctor to get a telephone prescription.
If the ad says. "No Prescription Needed", that’s a bad sign. That means that you are probably dealing with an offshore internet pharmacy that sells anything to anyone. Just because a person has a website and a computer does not mean they should be trusted to sell Cialis online. Use good judgment when you buy Cialis online.
Who this site recommends & why we recommend them:
If you are looking for the authentic Brand Name Cialis, I recommend AccessRx.com. They do not sell generic Cialis, which is good considering that it is illegal and dangerous to your health. AccessRx.com has been serving customers conveniently and safely since 1998. They are located in the USA in Tempe Arizona. Their customer service representatives are available 6-days a week and they have licensed physicians and pharmacists on staff to answer your medical questions.
AccessRx.com does have higher prices than generics but you are 100% assured that you will be getting the brand-name American, FDA-Approved Cialis delivered to your door conveniently in a couple of days without having to visit your own doctor.
1/10/08: A New Way To Take Cialis; Every Single Day!
Beginning in January of 2008, Lilly began marketing Cialis in a different manner. Cialis became approved for every day low-dose administration as an option for men with erectile dysfunction who engage in sex frequently (more than twice per week) so that men can engage in sex any time between doses rather than waiting for a pill to kick in.
Cialis for every-day-administration is given in a lower dose – 2.5mg to start (as opposed to the 10mg or 20mg that occasional users take). If the 2.5mg per day is inadequate, the dose can be doubled to 5mg per day. Your Cialis cost for a week’s worth of low dose therapy is comparable for what a man would pay if he takes two tablets per week. The cost of Cialis, unfortunately, has increased to more than $25 per pill, but that’s still better than risking your health by taking illegal “generic” Cialis.
Cialis is available 2.5mg, 5mg, 10mg and 20mg tablets.
If you are going to take Cialis the traditional way, every once in a while in anticipation of having sex, the recommended dose is 10mg taken prior to anticipated sexual activity without regard to food. In those patients in whom 10mg does not produce an adequate effect, 20mg might be tried.
It can be taken from 30 minutes to 12 hours prior to sexual activity. The efficacy of tadalafil may persist up to 24 hours post-dose. The maximum recommended dose of the 10mg or 20mg tablets is one pill per day.
How Does Cialis Work?
When an erection goes limp, you have PDE5 to thank.
Specialized penis tissue produces a substance called cyclic guanosine monophosphate (cGMP) in response to sexual stimulation. The more cGMP available, the more Durable the erection. Cialis inhibits the PDE5 enzyme, preserving cGMP levels, therefore aiding erection viability and durability.
Cialis is a member of a family of drugs known as PDE5 enzyme inhibitors.
Cialis is known as the “36 hour pill” or the “weekend pill” because unlike other similar drugs, Cialis has a long duration of action.
Cialis blocks an enzyme that causes an erection to go flaccid. Although Cialis is similar to Levitra and Viagra, its dose, onset of action, and duration of action is unique.
Cialis is a member of a family of drugs called PDE5 Inhibitors. Cialis is now marketed in approximately 40 countries and is available by prescription in pharmacies on five continents.
Cialis was developed by Icos, a small biotech company located in Washington State. Icos formed a 50/50 joint venture with Eli Lilly & company. Eventually, Lilly bought out Icos.
The BIG Discovery: cyclic guanosine monophosphate (cGMP)
When a man gets sexually stimulated, a chain reaction occurs in the tissue of the penis that results in elevated levels of a substance called cyclic guanosine monophosphate (cGMP).
As long as there are sufficient levels of cGMP, the penis can remain erect. The more cGMP, the more robust and durable the erection.
If you inhibit the degradation of cGMP it stays around in the penis longer, producing a more durable erection.
Cialis is that it preserves the elevated levels of cGMP that are created when a man is sexually stimulated for a stronger, more durable erection.
Cialis blocks the enzyme phosphodiesterase-5 (PDE5) which is responsible for the neutralization of cGMP. Cialis (tadalafil) is a highly selective inhibitor of PDE5. (PDE5 is not the only phosphodiesterase involved in the erectile physiology but it appears to be the most important one).
The nice thing about Cialis is that it won’t cause erections at inappropriate times because it only blocks degradation of cGMP produced in reaction to sexual stimulation, such as thinking about something sexy. If you are not being sexually stimulated, there is no cGMP to protect, so the drug remains in the background.
How Does Cialis Compare To Viagra and Levitra?
One huge difference is that Cialis is used to tread erectile dysfunction as though it is a chronic condition. As stated above, only Cialis is approved by the FDA to be taken once-per-day whether or not you are going to engage in sex. Viagra, on the other hand, is only taken just before sex. Here is a complete table that shows the difference between Viagra, Cialis, and Levitra.
Cialis Versus Viagra
Cialis Versus Viagra From Forbes magazine 12/03/03; M. Herper; side by side comparison of various characteristics of Cialis and Viagra in slide show format.
Cialis Versus Viagra Versus Levitra (2004 Media Report)
Viagra Faces Stiff Competition On Airwaves � Viagra focuses on depicting happy men in their ads. Levitra uses a woman’s testimonial and sports star Mike Ditka. Cialis, which is more subtle and longer-lasting, focuses on the relationship. [ WFTV.com]
Editor’s Note: Above report offers comparison between Cialis, Viagra and Levitra in terms of advertising.
Absorption, Onset, Bioavailability
Cialis is readily absorbed from the bloodstream. It is about 16% bioavailable. Tadalafil is about 94% bound to plasma protein. Maximum plasma concentration of Tadalafil was achieved 2 hours post dose. The Cialis label states that It can be taken from 30 minutes to 12 hours prior to sexual activity. Efficacy of tadalafil may persist up to 24 hours post-dose.
Metabolism, Half Life, Excretion
Cialis is mostly metabolized in the liver by an enzyme known as CYP3A4 and to a lesser extent CYPC2. Tadalafil breakdown products are excreted in the feces (61%) and in the urine (36%). Cialis’ mean half life is 17.5 hours in healthy men.
If you are going to take any of the PDE5 inhibitors such as Cialis, it is very important that your doctor be aware if you have a liver condition (such as cirrhosis) or kidney condition ( such as if you are on dialysis) because you may need a special dosage adjustment.
Likewise, if you try to buy Cialis online, please make sure that the person authorizing your prescription knows the true status of your liver function and your kidney function.
Non-Sexual Uses Of Cialis (tadalafil):
Benign Prostate Enlargement:
Recent information published in scientific journals indicate that Cialis may be useful for treating lower urinary tract symptoms associated with benign enlargement of the prostate. Of the doses studied, the 5 mg Cialis dose seemed to be the most appropriate dose.
See Also: J Urol. 2008 Aug 21. (abstract). CONCLUSIONS: Once daily tadalafil demonstrated clinically meaningful and statistically significant efficacy and it was well tolerated in men with benign prostatic hyperplasia lower urinary tract symptoms.
See Also: Impotence Drug Eases Prostate Problems. new research, funded by Eli Lilly, the company that owns the rights to the drug tadalafil, shows a daily dose of the drug may help ease some of the urinary symptoms related to an enlarged prostate. [WebMD]
Altitude Sickness
Because of Cialis’ effect on the cardiovascular system, researchers are looking into if it is beneficial to administer Cialis it to people who are susceptible to high altitude sickness. Early data indicates it has a moderate beneficial effect:
See Also: Am J Physiol Heart Circ Physiol. 2008 Apr;294(4):H1651-7. Epub 2008 Feb 29. Evidence supportive of impaired myocardial blood flow reserve at high altitude in subjects developing high-altitude pulmonary edema.
See Also: Ann Intern Med. 2006 Oct 3;145(7):497-506. Both tadalafil and dexamethasone may reduce the incidence of high-altitude pulmonary edema: a randomized trial �[ Annals of Internal Medicine; Abstract]
See Also: Stroke. 2005 Mar;36(3):557-60. Epub 2005 Feb 3. Effects of high altitude exposure on cerebral hemodynamics in normal subjects �[Stroke; Abstract]
Cialis Price Check. 10 top sites that sell Cialis; simple comparison shopping.
Cialis.com. Brand new website; prescribing information, patient information, safety information, FAQ, etc.
Cialis Prescribing Information. Dose, mechanism of action, side effects, precautions, warnings; patient information; very technical, don’t get scared when you come to the section on warnings and side effects. [ This is the information that doctors will use when they are considering prescribing Cialis]
Cialis Side Effects & Drug Interactions. 2,800 word report regarding side effects and drug interactions taken from Cialis’ official FDA label; includes seven charts and graphs.
Cialis Recall Information – up to date information regarding possible Cialis recalls if appropriate.*
* There has never been a Cialis recall so this page should be blank.
FDA Cialis Page. Cialis talk paper, Cialis label, Cialis approval letter, Questions and answers for Cialis, Cialis consumer drug information sheet.
Cialis Talk Paper [FDA]. from FDA’s official website; explains how Cialis is different from other erectile dysfunction drugs, starting dose, metabolism, possible drug interactions, contraindications.
Cialis Questions & Answers [FDA]. what is Cialis used for, how does it work, how is it different from similar drugs, how do you take cialis, common doses, etc. Similar to the drugtore flyer you get when you pick up a prescription at the drugstore.
Cialis Scientific Papers (from the National Library of medicine) automated Medline search; a listing of scientific papers in abstract form regarding Cialis.
Cialis News (from Google) recently published news regarding Cialis.
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